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SR-4370

Cat. No. M9890
SR-4370 Structure
Synonym:

SR4370

Size Price Availability Quantity
5mg USD 143  USD143 In stock
10mg USD 237  USD237 In stock
25mg USD 437  USD437 In stock
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

SR-4370 is a potent HDAC inhibitor.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 304.33
Formula C17H18F2N2O
CAS Number 1816294-67-3
Purity >99%
Solubility DMSO ≥ 90 mg/mL
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: SR-4370, SR4370 supplier, HDAC, inhibitors

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