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Specnuezhenide

Cat. No. M4523

All AbMole products are for research use only, cannot be used for human consumption.

Specnuezhenide Structure
Size Price Availability Quantity
5mg USD 60  USD60 In stock
10mg USD 100  USD100 In stock
20mg USD 150  USD150 In stock
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Quality Control & Documentation
Biological Activity

Specnuezhenide ((8E)-Nuezhenide) was separated from the fruit of the ligustrum lucidum. Specnuezhenide ((8E)-Nuezhenide) inhibited IL-1β -induced chondrocyte inflammation by inhibiting NF-κB and WNT /β-catenin signaling. Specnuezhenide ((8E)-Nuezhenide) showed anti-inflammatory effects in rat models of osteoarthritis (OA).

Chemical Information
Molecular Weight 686.66
Formula C31H42O17
CAS Number 39011-92-2
Solubility (25°C) DMSO ≥ 100 mg/mL
Storage 4°C, protect from light, dry, sealed
References

[1] Dongmei Hu, et al. Specnuezhenide reduces carbon tetrachloride-induced liver injury in mice through inhibition of oxidative stress and hepatocyte apoptosis

[2] Jing Yang, et al. Protective effect of Specnuezhenide on islet β cell of rats with gestational diabetes mellitus

[3] Yan Ding, et al. A validated LC-MS/MS method for the determination of specnuezhenide and salidroside in rat plasma and its application to a pharmacokinetic study

[4] Chiyuan Ma, et al. Specnuezhenide Decreases Interleukin-1β-Induced Inflammation in Rat Chondrocytes and Reduces Joint Destruction in Osteoarthritic Rats

[5] Hui-Fen Li, et al. Comparation of gastrointestinal absorption studies of specnuezhenide with salidroside in rats

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Keywords: Specnuezhenide supplier, NF-κB, inhibitors, activators

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