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SPC 839 

Cat. No. M29340

All AbMole products are for research use only, cannot be used for human consumption.

SPC 839  Structure

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Quality Control & Documentation
Biological Activity

SPC 839 (compound 10) is an orally active inhibitor of AP-1 and NF-kB mediated transcriptional activation with IC50 of 0.008 μM.

Chemical Information
Molecular Weight 366.39
Formula C18H14N4O3S
CAS Number 219773-55-4
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Lynn Verstrepen, et al. Biochem Pharmacol. Receptor proximal kinases in NF-κB signaling as potential therapeutic targets in cancer and inflammation

[2] Na Ye, et al. J Med Chem. Small molecule inhibitors targeting activator protein 1 (AP-1)

[3] Chun-Ho Park, et al. Bioorg Med Chem Lett. Discovery of thienopyrimidine-based FLT3 inhibitors from the structural modification of known IKKβ inhibitors

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  Catalog
Abmole Inhibitor Catalog




Keywords: SPC 839  supplier, NF-κB, inhibitors, activators

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