Free shipping on all orders over $ 500

Sp-cAMPS sodium salt 

Cat. No. M28396

All AbMole products are for research use only, cannot be used for human consumption.

Sp-cAMPS sodium salt  Structure

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.

Quality Control & Documentation
Biological Activity

Sp-cAMPS sodium salt, a cAMP analog, is potent activator of cAMP-dependent PKA I and PKA II. Sp-cAMPS sodium salt is also a potent, competitive phosphodiesterase (PDE3A) inhibitor with a Ki of 47.6 µM. Sp-cAMPS sodium salt binds the PDE10 GAF domain with an EC50 of 40 μM.

Chemical Information
Molecular Weight 367.25
Formula C10H11N5NaO5PS
CAS Number 142439-95-0
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Water 86.67 mg/mL (ultrasonic)
Storage -20°C, protect from light, dry, sealed
References

[1] Christopher L Brett, et al. J Physiol. Regulation of Cl--HCO3- exchangers by cAMP-dependent protein kinase in adult rat hippocampal CA1 neurons

[2] Rüdiger Popp, et al. Circ Res. Dynamic modulation of interendothelial gap junctional communication by 11,12-epoxyeicosatrienoic acid

[3] G A Smith, et al. J Physiol. Effects of noradrenaline on intracellular pH in acutely dissociated adult rat hippocampal CA1 neurones

[4] A V Chibalin, et al. J Biol Chem. Phosphorylation of the catalyic alpha-subunit constitutes a triggering signal for Na+,K+-ATPase endocytosis

[5] B Frohnwieser, et al. J Physiol. Modulation of the human cardiac sodium channel alpha-subunit by cAMP-dependent protein kinase and the responsible sequence domain

Related PKA Products
8-CPT-Cyclic AMP sodium

8-CPT-Cyclic AMP (8-CPT-cAMP) sodium is a selective activator of cyclic AMP-dependent protein kinase (PKA).
PKA-IN-1 

PKA-IN-1 is a potent and selective cyclic AMP-dependent protein kinase (PKA) catalytic subunit (cAK) inhibitor with an IC50 of 0.03 μM.
Sp-8-CPT-cAMPS 

Sp-8-CPT-cAMPS, a cAMP analog, is a potent and selective activator of the cAMP-dependent protein kinas A (PKA I and PKA II).
6-Bnz-cAMP sodium salt 

6-Bnz-cAMP sodium salt is a cell-permeable cAMP analog.
CW 008

CW 008 is a CREB or PKA pathway agonist. CW 008 also is a stem cell differentiating agent. CW008 promotes osteogenesis by activating cAMP/PKA/CREB signaling pathway and inhibiting leptin secretion. CW 008 stimulates osteoblast differentiation of human MSCs and increases bone formation in ovariectomized mice.

  Catalog
Abmole Inhibitor Catalog




Keywords: Sp-cAMPS sodium salt  supplier, PKA, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
Get to Know Us
Customer Support
Resources
Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.