Certificate of Analysis
| Product Name: | Sp-cAMPS sodium salt |
| Catalog Number: | M28396 |
| CAS Number: | 142439-95-0 |
Physical and Chemical Properties
| Formula: | C10H11N5NaO5PS |
| Molecular Weight: | 367.25 |
| Form: | Solid |
| Solubility: | DMSO 100 mg/mL (ultrasonic); Water 86.67 mg/mL (ultrasonic) |
| Storage: | -20°C, protect from light, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Sp-cAMPS sodium salt, a cAMP analog, is potent activator of cAMP-dependent PKA I and PKA II. Sp-cAMPS sodium salt is also a potent, competitive phosphodiesterase (PDE3A) inhibitor with a Ki of 47.6 µM. Sp-cAMPS sodium salt binds the PDE10 GAF domain with an EC50 of 40 μM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |