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Soblidotin

Cat. No. M13688

All AbMole products are for research use only, cannot be used for human consumption.

Soblidotin Structure
Synonym:

Auristatin PE; TZT-1027

Price and Availability

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Quality Control & Documentation
Biological Activity

Soblidotin (Auristatin PE) is a novel synthetic Dolastatin 10 derivative and inhibitor of tubulin polymerization.

*The compound is unstable in solutions, freshly prepared is recommended



Chemical Information
Molecular Weight 701.98
CAS Number 149606-27-9
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Junichi Watanabe, et al. Anticancer Drugs. Comparison of the antivascular and cytotoxic activities of TZT-1027 (Soblidotin) with those of other anticancer agents

[2] Junichi Watanabe, et al. Anticancer Res. Antitumor activity of TZT-1027 (Soblidotin)

[3] Tsugitaka Natsume, et al. Anticancer Res. Combination effect of TZT-1027 (Soblidotin) with other anticancer drugs

[4] M Bays, et al. Methods Find Exp Clin Pharmacol. Gateways to clinical trials

[5] Svetlana O Doronina, et al. Nat Biotechnol. Development of potent monoclonal antibody auristatin conjugates for cancer therapy

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Keywords: Soblidotin, Auristatin PE; TZT-1027 supplier, Microtubule, inhibitors, activators

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