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SHA 68 is a potent and selective non-peptide neuropeptide S receptor (NPSR) antagonist with IC50 values of 22.0 and 23.8 nM for NPSR Asn107 and NPSR Ile107, respectively. SHA 68 has limited the blood-brain barrier (BBB) penetration and the activity in neuralgia.
| Molecular Weight | 445.49 |
| Formula | C26H24FN3O3 |
| CAS Number | 847553-89-3 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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