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Scopolamine is a high affinity (nM) muscarinic antagonist. Scopolamine reversibly inhibited 5-HT3 receptor-responses with an IC50 of 2.09 μM.
| Molecular Weight | 303.35 |
| Formula | C17H21NO4 |
| CAS Number | 51-34-3 |
| Form | Melting point 55°C |
| Solubility (25°C) | DMSO 60 mg/mL |
| Storage | 4°C, sealed |
[1] Eran Galili, et al. Clin Oral Investig. Long-term scopolamine treatment and dental caries
| Related 5-HT Receptor Products |
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Tegaserod is an orally active serotonin receptor 4 (5-HT4R) agonist and a 5-HT2B receptor antagonist. Tegaserod has pKis of 7.5, 8.4 and 7.0 for human recombinant 5-HT2A, 5-HT2B and 5-HT2C receptors, respectively. Tegaserod causes tumor cell apoptosis, blunts PI3K/Akt/mTOR signaling and decreases S6 phosphorylation. |
| cis-Urocanic acid
cis-Urocanic acid is a 5-HT2A receptor agonist. cis-Urocanic acid binds to 5-HT receptor with relatively high affinity (Kd=4.6 nM). cis-Urocanic acid is also an immune modulator that induces immunosuppression. |
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