Free shipping on all orders over $ 500

Schizandrin-B

Cat. No. M4245

All AbMole products are for research use only, cannot be used for human consumption.

Schizandrin-B Structure
Synonym:

Schizandrin-B; Wuweizisu-B; gamma-Schisandrin

Size Price Availability Quantity
5mg USD 80  USD80 In stock
10mg USD 120  USD120 In stock
20mg USD 180  USD180 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Schisandrin B (γ-Schisandrin) isa diphenyl cycloctadiene derivative isolated from schisandra chinensis and has been shown to have antioxidant effects on the liver and heart of rodents.

Chemical Information
Molecular Weight 400.46
Formula C23H28O6
CAS Number 61281-37-6
Solubility (25°C) DMSO ≥ 80 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Bo Zhao, et al. Schizandrin B attenuates hypoxia/reoxygenation injury in H9c2 cells by activating the AMPK/Nrf2 signaling pathway

[2] Ling Cheng, et al. Schizandrin B Mitigates Rifampicin-Induced Liver Injury by Inhibiting Endoplasmic Reticulum Stress

[3] Jianjun Xu, et al. Schizandrin B protects LPS-induced sepsis via TLR4/NF-κB/MyD88 signaling pathway

[4] Yanli Lu, et al. Interaction of deoxyschizandrin and schizandrin B with liver uptake transporters OATP1B1 and OATP1B3

[5] Valrian Bunel, et al. Protective effects of schizandrin and schizandrin B towards cisplatin nephrotoxicity in vitro

Related Autophagy Products
NEO214

NEO214 is an autophagy inhibitor and a covalent conjugate of the PDE4 inhibitor Rolipram and perillyl alcohol. NEO214 has anti-cancer activity and blood-brain barrier (BBB) permeability. NEO214 prevents autophagy-lysosome fusion, thereby blocking autophagic flux and triggering glioma cell death.

Ammonium chloride-15N

Ammonium chloride-15N is the 15N labeled Ammonium chloride. Ammonium chloride is an autophagy inhibitor. Ammonium chloride is also a lysosome inhibitor.

Vacuolin-1

Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane. Vacuolin-1 blocks the Ca2+-dependent exocytosis of lysosomes and prevents the release of lysosomal content without affecting the process of resealing. vacuolin‐1 is a potent and selective PIKfyve inhibitor and inhibits late‐stage autophagy by impairing lysosomal maturation.

CA77.1 

CA77.1 is a potent, brain-penetrant and orally active chaperone-mediated autophagy (CMA) activator with favorable pharmacokinetics.

KAN0438757 

KAN0438757 is a potent and selective inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.

  Catalog
Abmole Inhibitor Catalog




Keywords: Schizandrin-B, Schizandrin-B; Wuweizisu-B; gamma-Schisandrin supplier, Autophagy, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.