All AbMole products are for research use only, cannot be used for human consumption.
SB756050 is a selective TGR5 agonist. SB756050 has the potential for type 2 diabetes treatment.
| Molecular Weight | 500.59 |
| CAS Number | 447410-57-3 |
| Solubility (25°C) | DMSO ≥ 100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related GPCR19/TGR5 Products |
|---|
| Ursodeoxycholic acid sodium
Ursodeoxycholic acid (Ursodeoxycholate) sodium is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. |
| Deoxycholic acid sodium salt
Deoxycholic acid sodium salt activates the G protein-coupled bile acid receptor TGR5. |
| SBI-115
SBI-115 is a TGR5 (GPCR19) antagonist, it decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5. |
| INT-777
INT-777 is a potent TGR5 agonist with EC50 of 0.82 μM. |
| BAR 502
BAR502 is a dual agonist of FXR and GPBAR1 with IC50 values of 2 μM and 0.4 μM, respectively. |
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