|M13985||Ursodeoxycholic acid sodium||Ursodeoxycholic acid (Ursodeoxycholate) sodium is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism.|
|M11152||Deoxycholic acid sodium salt||Deoxycholic acid sodium salt activates the G protein-coupled bile acid receptor TGR5.|
|M9727||SBI-115||SBI-115 is a TGR5 (GPCR19) antagonist, it decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5.|
|M9055||INT-777||INT-777 is a potent TGR5 agonist with EC50 of 0.82 μM.|
|M5256||BAR 502||BAR502 is a dual agonist of FXR and GPBAR1 with IC50 values of 2 μM and 0.4 μM, respectively.|
|M2588||TGR5 Receptor Agonist||TGR5 Receptor Agonist is a potent TGR5(GPCR19) agonist which showed improved potency in the U2-OS cell assay (pEC50 = 6.8) and in melanophore cells (pEC50 = 7.5).|
|M13984||SB756050||SB756050 is a selective TGR5 agonist. SB756050 has the potential for type 2 diabetes treatment.|
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