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Sabarubicin

Cat. No. M29252

All AbMole products are for research use only, cannot be used for human consumption.

Sabarubicin Structure
Synonym:

MEN 10755

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Quality Control & Documentation
Biological Activity

Sabarubicin is a doxorubicin disaccharide analogue with striking antitumor activity. Sabarubicin is more effective than doxorubicin as a topoisomerase II poison and stimulated DNA fragmentation at lower intracellular concentrations.

Chemical Information
Molecular Weight 643.64
Formula C32H37NO13
CAS Number 211100-13-9
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Federico-Maria Arcamone. Top Curr Chem. Sabarubicin

[2] Alessandro Bressan, et al. Anticancer Res. Sabarubicin (MEN10755)-induced apoptosis is independent from mtDNA in A2780 human ovarian tumor cells

[3] M Bigioni, et al. Cancer Chemother Pharmacol. Antitumour effect of combination treatment with Sabarubicin (MEN 10755) and cis-platin (DDP) in human lung tumour xenograft

[4] Daniela Bellarosa, et al. Anticancer Res. Sabarubicin- (MEN 10755) and paclitaxel show different kinetics in nuclear factor-kappaB (NF-kB) activation: effect of parthenolide on their cytotoxicity

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  Catalog
Abmole Inhibitor Catalog




Keywords: Sabarubicin, MEN 10755 supplier, Topoisomerase, inhibitors, activators

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