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(S)-UFR2709 (hydrochloride) is a competitive nAChR antagonist and displays higher affinity for α4β2 nAChRs than for α7 nAChRs. (S)-UFR2709 (hydrochloride) decreases anxiety and reduces ethanol consumption and ethanol preference in alcohol-preferring rats. (S)-UFR2709 (hydrochloride) acts as an anxiolytic agent and can be used for the study of nicotine addiction.
| Molecular Weight | 255.74 |
| Formula | C13H18ClNO2 |
| Form | Solid |
| Solubility (25°C) | Water 100 mg/mL (ultrasonic) DMSO 50 mg/mL (ultrasonic) |
| Storage | 4°C, sealed |
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