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(S)-C33 

Cat. No. M29156

All AbMole products are for research use only, cannot be used for human consumption.

(S)-C33  Structure

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Quality Control & Documentation
Biological Activity

(S)-C33 is a potent and selective PDE9 (phosphodiesterase-9) inhibitor, with an IC50 of 11 nM. (S)-C33 can be used for central nervous system diseases and diabetes research.

Chemical Information
Molecular Weight 357.84
Formula C18H20ClN5O
CAS Number 2066488-39-7
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Pan-Xia Wang, et al. Acta Pharmacol Sin. C33(S), a novel PDE9A inhibitor, protects against rat cardiac hypertrophy through upregulating cGMP signaling

[2] Manna Huang, et al. Mol Pharmacol. Structural Asymmetry of Phosphodiesterase-9A and a Unique Pocket for Selective Binding of a Potent Enantiomeric Inhibitor

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  Catalog
Abmole Inhibitor Catalog




Keywords: (S)-C33  supplier, PDE, inhibitors, activators

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