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Rubitecan

Cat. No. M20696

All AbMole products are for research use only, cannot be used for human consumption.

Rubitecan Structure
Synonym:

9-NC, 9-Nitro-camptothecin, Partaject Orathecin, Partaject rubitecan, RFS 2000

Size Price Availability Quantity
5mg USD 75  USD75 In stock
10mg USD 100  USD100 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Rubitecan is a topoisomerase I inhibitor extracted from the bark and leaves of the Camptotheca acuminata tree, which is native to China. Rubitecan is an oral camptothecin with antitumour activity.

Chemical Information
Molecular Weight 393.35
Formula C20H15N3O6
CAS Number 91421-42-0
Solubility (25°C) DMSO 58 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jeffrey W Clark. Expert Opin Investig Drugs. Rubitecan

[2] No authors listed. Drugs R D. Rubitecan: 9-NC, 9-Nitro-20(S)-camptothecin, 9-nitro-camptothecin, 9-nitrocamptothecin, RFS 2000, RFS2000

[3] P M Fracasso, et al. Ann Oncol. Phase I study of rubitecan and gemcitabine in patients with advanced malignancies

[4] Howard Sands, et al. Anticancer Drugs. Preclinical activity of an i.v. formulation of rubitecan in IDD-P against human solid tumor xenografts

[5] Beppino C Giovanella, et al. Int J Oncol. Preclinical evaluation of the anticancer activity and toxicity of 9-nitro-20(S)-camptothecin (Rubitecan)

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  Catalog
Abmole Inhibitor Catalog




Keywords: Rubitecan, 9-NC, 9-Nitro-camptothecin, Partaject Orathecin, Partaject rubitecan, RFS 2000 supplier, Topoisomerase, inhibitors, activators

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