All AbMole products are for research use only, cannot be used for human consumption.
Ripretinib (DCC-2618) is an orally bioavailable, selective KIT and PDGFR-alpha inhibitor. Ripretinib (DCC-2618) suppresses phosphorylation of KIT and decreases the expression of phosphosphorylated (p)STAT5, pAKT and pERK1/2 in neoplastic mast cells.
| Molecular Weight | 510.36 |
| Formula | C24H21BrFN5O2 |
| CAS Number | 1442472-39-0 |
| Solubility (25°C) | DMSO 32 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Cancer Discov. BLU-285, DCC-2618 Show Activity against GIST
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