All AbMole products are for research use only, cannot be used for human consumption.
Granzyme B (GZMB) is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Recombinant Mouse Granzyme B expressed the target gene encoding Gly19-Ser247 with a 6His tag at the C-terminus.
Accession: P04187
Endotoxin < 1 EU/µg
Apparent Molecular Weight: 35 KDa, reducing conditions
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
The product is shipped on dry ice packs. Upon receipt, store it immediately at the temperature listed below.
| Form | Solution |
| Storage | Store at ≤ -70°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
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Products are for research use only. Not for human use. We do not sell to patients.
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