Free shipping on all orders over $ 500

Recombinant Mouse Granzyme B (HEK293, C-6His)

Cat. No. M58590

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Mouse Granzyme B (HEK293, C-6His) Structure
Synonym:

Gzmb

Size Price Availability Quantity
10ug USD 300  USD300 In stock
50ug USD 900  USD900 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
  • Purity: >95%, Endotoxin < 1 EU/µg
  • COA
  • MSDS
Biological Activity

Granzyme B (GZMB) is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. 

Recombinant Mouse Granzyme B expressed the target gene encoding Gly19-Ser247 with a 6His tag at the C-terminus.


Accession: P04187

Endotoxin < 1 EU/µg

Apparent Molecular Weight: 35 KDa, reducing conditions

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

The product is shipped on dry ice packs. Upon receipt, store it immediately at the temperature listed below.

Chemical Information
Form Solution
Storage Store at ≤ -70°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Related Cytokines and Growth Factors Products
Recombinant Human GDF-15 Protein (HEK293 N-hFc)

Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily. GDF-15 has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF-15 overexpression arising from an expanded erythroid compartment contributes to iron overload in thalassemia syndromes by inhibiting hepcidin expression.

Recombinant Human FGFR1 Protein (HEK293, C-His)

FGFR1, also known as CD331, is a full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain.

Recombinant Human FGFR2 Protein (HEK293, C-His)

FGFR2, also known as CD332, acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. FGFR2 plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. It also promotes cell proliferation in keratinocytes and imature osteoblasts, but promotes apoptosis in differentiated osteoblasts.

Recombinant Mouse BMP-4 Protein (E. coli, C-His)

Bone Morphogenetic Protein-4 (BMP-4) is a critical signaling molecule required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. BMP-4 is secreted from the dorsal portion of the notochord, and it acts in concert with sonic hedgehog to establish a dorsal-ventral axis for the differentiation of later structures.

Recombinant Human Coagulation Factor X (HEK293, C-Fc)

Coagulation factor X, belongs to the peptidase S1 family. Coagulation factor X is initially synthesized in the liver. Coagulation factor X is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.

  Catalog
Abmole Inhibitor Catalog




Keywords: Recombinant Mouse Granzyme B (HEK293, C-6His), Gzmb supplier, Cytokines and Growth Factors, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.