Certificate of Analysis
| Product Name: | Recombinant Mouse Granzyme B (HEK293, C-6His) |
| Catalog Number: | M58590 |
Physical and Chemical Properties
| Form: | Solution |
| Storage: | Store at ≤ -70°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
Analytical Data
| QC Standard: | >95%, Endotoxin < 1 EU/µg |
Product Information
| Description: | Granzyme B (GZMB) is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |