All AbMole products are for research use only, cannot be used for human consumption.
Recombinant Human VEGF165 Protein (HEK293, C-His) is a powerful growth and angiogenic cytokine. It promotes the proliferation and survival of endothelial cells, promotes angiogenesis and vascular permeability. VEGF is expressed in vascularized tissues and plays an important role in normal and pathological angiogenesis.
Measured by human umbilical vein endothelial cells (HUVEC) proliferation assay, the ED50 for this effect is ≤20 ng/mL.
DNA sequence encoding human VEGF165 (NP_001165097.1) is expressed with a His tag at the C terminus.
The recombinant human VEGF165 protein contains 193 amino acids and has a predicted theoretical molecular weight of 22.3 kD.
Endotoxin <0.1EU/μg
Cell Death Dis. 2023 Mar 11;14(3):194.
USP22 upregulates ZEB1-mediated VEGFA transcription in hepatocellular carcinoma
Recombinant Human VEGF165 Protein (HEK293, C-His) purchased from AbMole
Sci Rep. 2019 Nov 28;9(1):17745.
In vivo delivery of VEGF RNA and protein to increase osteogenesis and intraosseous angiogenesis
Recombinant Human VEGF165 Protein (HEK293, C-His) purchased from AbMole
| Solubility (25°C) | Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
| Related Cytokines and Growth Factors Products |
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Bone Morphogenetic Protein-4 (BMP-4) is a critical signaling molecule required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. BMP-4 is secreted from the dorsal portion of the notochord, and it acts in concert with sonic hedgehog to establish a dorsal-ventral axis for the differentiation of later structures. |
| Recombinant Human Coagulation Factor X (HEK293, C-Fc)
Coagulation factor X, belongs to the peptidase S1 family. Coagulation factor X is initially synthesized in the liver. Coagulation factor X is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting. |
| Recombinant Human FGF-8b Protein (E. coli)
Recombinant Human FGF-8b Protein is a heparin-binding growth factor, which plays a core role in prenatal development, postnatal growth and regeneration of various tissues by promoting cell proliferation and other effect. |
| Recombinant Rat GDNF Protein (Baculovirus-Insect, N-His)
GDNF is an important member of the GDNF family of ligands. GDNF plays a key role in the promotion of the survival of dopaminergic neurons. GDNF is a highly conserved neurotrophic factor. The recombinant form of this protein also promotes the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. GDNF also regulates kidney development and spermatogenesis, and it affects alcohol consumption. |
| Recombinant Rat PDGF-BB (E. coli)
Platelet-Derived Growth Factor-BB (PDGF-BB) is one of five dimers (PDGF-AA, AB, BB, CC, and DD) formed by 4 different PDGF subunits. PDGF-BB functions in a paracrine manner and promotes organogenesis, human skeletal development, and wound healing. PDGF-BB also promotes angiogenesis, particularly in the presence of Fibroblast Growth Factor basic. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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