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VCAM-1 is a single-pass type I membrane protein, and mediates leukocyte-endothelial cell adhesion and signal transduction. VCAM-1 also activates signals within endothelial cells resulting in the opening of an "endothelial cell gate" through which leukocytes migrate. In addition, VCAM-1-activated signals in endothelial cells are regulated by cytokines indicating that it is important to consider both endothelial cell adhesion molecule expression and function during inflammatory processes.
Recombinant Human VCAM-1 Protein expressed the target gene encoding Phe25-Glu698 with a human IgG1 Fc tag at the C-terminus.
Accession: P19320
Endotoxin < 1 EU/µg
Apparent Molecular Weight: 115-145 kDa, reducing conditions
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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