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Species: Human
Expression system: E. coli
Purity: SDS-PAGE analysis > 95%, HPLC analysis > 95%
Endotoxin: Protein content < 0.2 EU/μg was determined by gel coagulation
Apparent molecular weight: ~19.4 kDa, reduced by SDS-PAGE
Storage and stability: Upon receipt, the product remains stable at temperatures below -70°C for up to 6 months. After reconstruction, the product should be stable at 4°C for up to 1 week or at -20°C for up to 3 months. For long-term storage, the addition of a carrier protein (e.g. 0.1% BSA) is recommended. Avoid repeated freeze-thaw cycles.
Bioactivity: ED50 < 0.5 ng/ml, measured in cell proliferation assay using 3T3 cells, corresponds to > 2.0 × 10 6 units /mg of specific activity. Fibroblast growth factor-4 (FGF-4), also known as K-FGF, is a heparin-bound growth factor in the FGF family. It is identified by its carcinogenic transforming activity. FGF-4 and FGF-3 are located on chromosome 11. FGF-4 and its receptors (FGF-R1C, 2c, 3c and 4) play an important role in the regulation of embryonic development, cell proliferation and cell differentiation. FGF-4 is required for normal limb and heart valve development during embryogenesis.
| Solubility (25°C) | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O up to 100 μg/ml. |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] No authors listed. BioDrugs. FGF-4 gene therapy GENERX--Collateral Therapeutics
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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