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Recombinant Human EGFR Protein (CHO, C-His)

Cat. No. M58101

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human EGFR Protein (CHO, C-His) Structure
Synonym:

ERBB; ERBB1; HER1; Epidermal Growth Factor Receptor

Size Price Availability Quantity
10ug USD 150  USD150 In stock
50ug USD 420  USD420 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 0.2 EU/µg
  • COA
  • MSDS
Biological Activity

EGFR, also known as ERBB, ERBB1 and HER1, is a type I transmembrane protein belonging to the tyrosine protein kinase family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. EGFR also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling.

Recombinant Human EGFR expressed the target gene encoding Leu25-Ser645 with a His tag at the C-terminus.

Measured in a bioassay using 3T3 cells in the presence of 25.0 pg/ml human EGF, the ED50 is < 1.0 μg/ml.


Accession: P00533

Apparent Molecular Weight: 95~115 KDa, reducing conditions

Endotoxin < 0.2 EU/µg

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
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Keywords: Recombinant Human EGFR Protein (CHO, C-His), ERBB; ERBB1; HER1; Epidermal Growth Factor Receptor supplier, Recombinant Proteins, inhibitors, activators

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