Certificate of Analysis
| Product Name: | Recombinant Human EGFR Protein (CHO, C-His) |
| Catalog Number: | M58101 |
Physical and Chemical Properties
| Form: | Lyophilized powder |
| Solubility: | Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml. |
| Storage: | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
Analytical Data
| QC Standard: | >95%, Endotoxin < 0.2 EU/µg |
Product Information
| Description: | EGFR, also known as ERBB, ERBB1 and HER1, is a type I transmembrane protein belonging to the tyrosine protein kinase family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. EGFR also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |