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CSF1R is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. CSF1R protein is ubiquitously found in mononuclear phagocytes, especially macrophages and monocytes, and is involved in a variety of biological processes. It induces the release of proinflammatory chemokines in response to IL34 and CSF1, contributing to innate immunity and inflammation.
Recombinant Human CSF1R expressed the target gene encoding Ile20-Pro517 with a 6His tag at the C-terminus.
Immobilized Recombinant Human CSF1R at 10 μg/ml (100 μl/well) can bind Biotinylated Human M-CSF, the ED50 for this effect is 0.26 μg/ml.
Accession: P07333
Apparent Molecular Weight: 80-110 KDa, under reducing conditions
Endotoxin < 1 EU/µg
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water to a concentration not less than 100 μg/mL. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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Products are for research use only. Not for human use. We do not sell to patients.
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