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CA125 is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. CA125 binds galectin-1 on immune cells and enhances its expression on tumor cells. CA125-expressing tumors adhere to NK cells, down-regulate CD16 and suppress NK response, which may promote immune evasion.
Recombinant Human CA125/Mucin-16 expressed the target gene encoding Gly12660-Met12923 with a 6His tag at the C-terminus.
Accession: Q8WXI7
Endotoxin < 1 EU/µg
Apparent Molecular Weight: 40-70 KDa, reducing conditions
Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCl, 100 mM Glycine, pH 7.5.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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Products are for research use only. Not for human use. We do not sell to patients.
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