Certificate of Analysis
| Product Name: | Recombinant Human CA125 Protein (HEK293, C-6His) |
| Catalog Number: | M55679 |
Physical and Chemical Properties
| Form: | Lyophilized powder |
| Solubility: | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage: | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
Analytical Data
| QC Standard: | >95%, Endotoxin < 1 EU/µg |
Product Information
| Description: | CA125 is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. CA125 binds galectin-1 on immune cells and enhances its expression on tumor cells. CA125-expressing tumors adhere to NK cells, down-regulate CD16 and suppress NK response, which may promote immune evasion. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |