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(rac)-AG-205 is a potent inhibitor of progesterone receptor membrane component 1 (Pgrmc1) that induces genes involved in sterol synthesis, including the INSIG1 protein, which forms a complex with PGRMC1. (rac)-AG-205 prevents neuronal resistance to hypoxic ischaemia by blocking NF-kB signalling and activation of the BDNF/PI3K/AKT pathway.
| Molecular Weight | 454.98 |
| Formula | C22H23ClN6OS |
| CAS Number | 442656-02-2 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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