Free shipping on all orders over $ 500

PythiDC 

Cat. No. M28927

All AbMole products are for research use only, cannot be used for human consumption.

PythiDC  Structure

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

PythiDC is a selective collagen prolyl 4-hydroxylase (CP4H1) inhibitor with an IC50 value of 4.0 μM. PythiDC can be used as a CP4H probe and also can be used for the development of a new class of antifibrotic and antimetastatic agents.

Chemical Information
Molecular Weight 250.23
Formula C10H6N2O4S
CAS Number 1821370-71-1
Form Solid
Solubility (25°C) DMSO 4.9 mg/mL (ultrasonic and warming and adjust pH to 4 with HCl and heat to 60°C)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Alyncia D Robinson, et al. Transl Oncol. Collagen modifying enzyme P4HA1 is overexpressed and plays a role in lung adenocarcinoma

[2] Sumit Agarwal, et al. Transl Oncol. Targeting P4HA1 with a Small Molecule Inhibitor in a Colorectal Cancer PDX Model

Related MMP Products
MMP2-IN-1

MMP2-IN-1 is a moderate potenet MMP2 inhibitor with IC50 of 6.8 µM. MMP2-IN-1 exhibits remarkable antiproliferative activity in certain cancer cells by arresting the cell cycle and inducing apoptosis.

MMP-9 Inhibitor I

MMP-9 inhibitor I is a cell-permeable, potent, selective, and reversible inhibitor of MMP-9 (IC50 = 5 nM). MMP-9 inhibitor I also inhibits MMP-1 (IC50 = 1.05 µM) and MMP-13 IC50 = 113 nM) at higher concentrations.

BPHA 

BPHA is a potent and orally active MMP-2, MMP-9 and MMP-14 inhibitor with IC50s of 12 nM, 16 nM and 17 nM, respectively.

ONO-4817 

ONO-4817 is a potent inhibitor of matrix metalloproteinase (MMP).

UK-370106 

UK-370106 is a potent and highly selective MMP-3 (IC50 of 23 nM) and MMP-12 (IC50 of 42 nM) inhibitor with >1200-fold higher potency than MMP-1, MMP-2, MMP-9, and MMP-14, and about 100-fold than MMP-13 and MMP-8.

  Catalog
Abmole Inhibitor Catalog




Keywords: PythiDC  supplier, MMP, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.