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Pronethalol ((±)-Pronethalo) is a non-selective β-adrenergic antagonist. Pronethalol is a potent inhibitor of Sox2 expression. Pronethalol protects against and to reverse Digitalis-induced ventricular arrhythmias and limits the cerebral arteriovenous malformation (AVMs).
| Molecular Weight | 229.32 |
| Formula | C15H19NO |
| CAS Number | 54-80-8 |
| Form | Solid |
| Solubility (25°C) | DMSO 50 mg/mL (ultrasonic) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] D N KERR. Br Med J. EFFECTS OF PRONETHALOL
[5] P A Bond, et al. Biochem Pharmacol. The metabolism of pronethalol
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