About 9 results found for searched term "54-80-8" (0.068 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1942 | Alectinib | ALK |
| CH5424802; AF802 | ||
| Alectinib (CH5424802) is a highly selective, orally active and potent ALK inhibitor with IC50 of 1.9 nM. Alectinib (CH5424802) also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. Alectinib demonstrates effective central nervous system (CNS) penetration. | ||
| M9175 | Vacquinol-1 | JNK |
| NSC13316 | ||
| Vacquinol-1 is an MKK4 activator, which rapidly and selectively induces glioma cell death. | ||
| M10848 | LP-922761 | Others |
| LP-922761 is a potent, selective, orally active AAK1 inhibitor in enzymatic and cell analysis IC50 4.8 nM and 7.6 nM, respectively. LP-922761 also inhibits BMP-2-induced protein kinase (BIKE),IC50 24 nM. LP-922761 has no significant activity against cell GAK, opioids, epinephrine alpha2, or GABAa receptors. | ||
| M16573 | 5-Hydroxy-7-acetoxy-8-methoxyflavone | Flavonoids |
| 5-Hydroxy-7-acetoxy-8-methoxyflavone | ||
| M19917 | Midecamycin | Antibiotic |
| Espinomycin A; Medecamycin A1; Platenomycin B1; Rubimycin; Turimycin P3; SF-837 | ||
| Midecamycin is a naturally occuring macrolide antibiotic that acts by inhibiting bacterial protein synthesis. | ||
| M21275 | ONO-8430506 | PDE |
| ONO-8430506 is a potent autotaxin phosphodiesterase inhibitor with significant oral exposure and low clearance in higher species. | ||
| M28055 | JNJ-46281222 | GluR |
| JNJ-46281222 is an metabotropic glutamate (mGlu) 2-selective, highly potent PAM (positive allosteric modulator) with nanomolar affinity (Kd = 1.7 nM) and a high modulatory potency (pEC50 = 7.71). | ||
| M30282 | Pronethalol | Adrenergic Receptor |
| (±)-Pronethalo | ||
| Pronethalol ((±)-Pronethalo) is a non-selective β-adrenergic antagonist. Pronethalol is a potent inhibitor of Sox2 expression. Pronethalol protects against and to reverse Digitalis-induced ventricular arrhythmias and limits the cerebral arteriovenous malformation (AVMs). | ||
| M53893 | DfTat | Others |
| DfTat is a dimer of the prototypical cell-penetrating peptide TAT. | ||
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