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Pomalidomide-piperazine 

Cat. No. M57112

All AbMole products are for research use only, cannot be used for human consumption.

Pomalidomide-piperazine  Structure

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Quality Control & Documentation
Biological Activity

Pomalidomide-piperazine is an active compound that can be used to synthesis the E3 ligand for PROTAC.

Chemical Information
Molecular Weight 342.35
Formula C17H18N4O4
CAS Number 2154342-57-9
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Related Ligand for E3 Ligase Products
OICR-8268

OICR-8268 is a reversible DCAF1 ligand that binds to the DCAF1 WDR domain with a Kd of 38 nM. OICR-8268 can be used in the development of DCAF1-based PROTACs.

BC-1215

BC-1215 is a novel inhibitor of F-box protein 3 (Fbxo3) activity. BC-1215 works by antagonizing of Fbxo3 on TRAF cytokine signaling and exhibits a low IC50 in vitro. BC-1215 relieves allodynia by preventing ubiquitination-dependent Fbxl2/TRAF2/TNIK/pGluR1 signaling. BC-1215 exerted robust therapeutic effects in cytokine-driven inflammation, including pseudomona-induced lung injury and cecum ligation/punctured-induced sepsis, by targeting Fbxo3/Fbxl2/TRAF-mediated cytokine release. BC-1215 can be used for the research of inflammation.

VH 101, acid 

VH 101, acid is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development.

(S,R,S)-AHPC-Boc

(S,R,S)-AHPC-Boc (VH032-Boc) is a ligand used in the recruitment of the von Hippel-Lindau (VHL) protein.

Lenalidomide-Br 

Lenalidomide-Br is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein.

  Catalog
Abmole Inhibitor Catalog




Keywords: Pomalidomide-piperazine  supplier, Ligand for E3 Ligase, inhibitors, activators

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