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Pinocembrin 7-O-glucoside

Cat. No. M16620
Pinocembrin 7-O-glucoside Structure
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Biological Activity

Pinocembrin 7-O-glucoside

Chemical Information
CAS Number 75829-43-5
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Mara Del Carmen Corts-Chitala, et al. Molecules. Identification and Quantification of Phenolic Compounds from Mexican Oregano ( Lippia graveolens HBK) Hydroethanolic Extracts and Evaluation of Its Antioxidant Capacity

[2] Evangelia Tsiokanos, et al. Food Chem. Phytochemical characteristics of bergamot oranges from the Ionian islands of Greece: A multi-analytical approach with emphasis in the distribution of neohesperidose flavanones

[3] Farieha Hussain, et al. Oxid Med Cell Longev. Identification of Hypotensive Biofunctional Compounds of Coriandrum sativum and Evaluation of Their Angiotensin-Converting Enzyme (ACE) Inhibition Potential

[4] Long-Ze Lin, et al. J Food Compost Anal. Identification and quantification of flavonoids of Mexican oregano ( Lippia graveolens) by LC-DAD-ESI/MS analysis

[5] Daniela M Biondi, et al. J Nat Prod. Dihydrostilbene derivatives from Glycyrrhiza glabra leaves

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