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Pim-1 kinase inhibitor 6

Cat. No. M42104

All AbMole products are for research use only, cannot be used for human consumption.

Pim-1 kinase inhibitor 6 Structure

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Quality Control & Documentation

Purity:
COA
MSDS

Product Information

Biological Activity

Pim-1 kinase inhibitor 6 is a potent Pim-1 kinase inhibitor with IC50 value of 0.46 μM, and has significant cytotoxic effect on cancer cells.

Chemical Information

Molecular Weight	455.13
Formula	C21H10BrCl2N3
CAS Number	2928606-69-1
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

References

[1] George Nicolae Daniel Ion et al. Life (Basel). A PIM-1 Kinase Inhibitor Docking Optimization Study Based on Logistic Regression Models and Interaction Analysis

[2] Mirosława Koronkiewicz et al. BMC Cancer. Antitumor activity of the protein kinase inhibitor 1-(β-D-2'-deoxyribofuranosyl)-4,5,6,7-tetrabromo- 1H-benzimidazole in breast cancer cell lines

[3] Ashley Y Gao et al. Am J Physiol Lung Cell Mol Physiol. Pim-1 kinase is a positive feedback regulator of the senescent lung fibroblast inflammatory secretome

[4] Seham S El-Hawary et al. Front Chem. New Pim-1 Kinase Inhibitor From the Co-culture of Two Sponge-Associated Actinomycetes

[5] Carmen Blanco-Aparicio et al. Cancer Lett. Pim 1 kinase inhibitor ETP-45299 suppresses cellular proliferation and synergizes with PI3K inhibition

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Catalog

Abmole Inhibitor Catalog

Keywords: Pim-1 kinase inhibitor 6 supplier, Pim, inhibitors, activators

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