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PHY34

Cat. No. M20638

All AbMole products are for research use only, cannot be used for human consumption.

PHY34 Structure

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Quality Control & Documentation
Biological Activity

PHY34 is a late-stage autophagy inhibitor with nanomolar potency and significant antitumor efficacy as a single agent against HGSOC in vivo.

Chemical Information
Molecular Weight 582.55
Formula C30H30O12
CAS Number 2130033-55-3
Solubility (25°C) DMSO 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Amrita Salvi, et al. Cell Death Dis. PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer

[2] Alexandria N Young, et al. Mol Cancer Ther. Phyllanthusmin Derivatives Induce Apoptosis and Reduce Tumor Burden in High-Grade Serous Ovarian Cancer by Late-Stage Autophagy Inhibition

[3] Jo De Vrieze, et al. Water Res. The full-scale anaerobic digestion microbiome is represented by specific marker populations

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Keywords: PHY34 supplier, Autophagy, inhibitors, activators

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