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Phenindione

Cat. No. M3348

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Phenindione Structure
Synonym:

Rectadione, phenylindandione

Size Price Availability Quantity
100mg USD 60  USD60 In stock
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Quality Control & Documentation
Biological Activity

Phenindione (Rectadione) is an anticoagulant which functions as a Vitamin K antagonist. A lymphocyte transformation test showed proliferation of T-cells from the hypersensitive patient, but not from four controls on exposure to phenindione in vitro. Drug-specific T-cell clones were generated and characterized in terms of their phenotype, functionality, and mechanism of antigen presentation. Forty-three human leukocyte antigen class II restricted CD4+ αβ T-cell clones were identified. T-cell activation resulted in the secretion of interferon-γ and interleukin-5.

Chemical Information
Molecular Weight 222.24
Formula C15H10O2
CAS Number 83-12-5
Solubility (25°C) DMSO 40 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] A Sankaralingam, et al. Phenindione interferes with measurement of creatinine

[2] P W COPEMAN. PHENINDIONE TOXICITY

[3] J B ROSS. Side-effect of phenindione

[4] J BINGLE, et al. Phenindione sensitivity

[5] P W Copeman. Side-effects of phenindione

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Keywords: Phenindione, Rectadione, phenylindandione supplier, inhibitors, activators

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