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Ph-HTBA 

Cat. No. M29547

All AbMole products are for research use only, cannot be used for human consumption.

Ph-HTBA  Structure

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Quality Control & Documentation
Biological Activity

Ph-HTBA is a high-affinity, brain-penetrating modulator for CaMKIIα. Ph-HTBA has binding affinity for CaMKIIα with a Kd value of 757 nM. Ph-HTBA can be used for the research of ischemia and neurodegenerative disorders.

Chemical Information
Molecular Weight 294.34
Formula C19H18O3
CAS Number 2368927-41-5
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Yongsong Tian, et al. J Med Chem. Exploring the NCS-382 Scaffold for CaMKIIα Modulation: Synthesis, Biochemical Pharmacology, and Biophysical Characterization of Ph-HTBA as a Novel High-Affinity Brain-Penetrant Stabilizer of the CaMKIIα Hub Domain

[2] Nane Griem-Krey, et al. Biomed Pharmacother. The CaMKIIα hub ligand Ph-HTBA promotes neuroprotection after focal ischemic stroke by a distinct molecular interaction

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  Catalog
Abmole Inhibitor Catalog




Keywords: Ph-HTBA  supplier, CaMK, inhibitors, activators

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