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PF 1022A 

Cat. No. M28191

All AbMole products are for research use only, cannot be used for human consumption.

PF 1022A  Structure

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Quality Control & Documentation
Biological Activity

PF 1022A is a cyclooctadepsipeptide with broadspectrum anthelmintic properties produced by fermentation of the fungus Mycelia sterilia. PF 1022A is a channel-forming ionophore. PF 1022A showes strong anthelmintic activities against Ascaridia galli in chickens. PF 1022A also can be used for angiostrongyliasis research.

Chemical Information
Molecular Weight 949.18
Formula C52H76N4O12
CAS Number 133413-70-4
Form Solid
Solubility (25°C) DMSO ≥ 43 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jürgen Krücken, et al. Trends Parasitol. Anthelmintic cyclcooctadepsipeptides: complex in structure and mode of action

[2] Peter Jeschke, et al. Pest Manag Sci. Synthesis of anthelmintically active N-methylated amidoxime analogues of the cyclic octadepsipeptide PF1022A

[3] H Zahner, et al. Int J Parasitol. Filaricidal efficacy of anthelmintically active cyclodepsipeptides

[4] G von Samson-Himmelstjerna, et al. Parasitol Res. In vivo activities of the new anthelmintic depsipeptide PF 1022A

[5] T G Geary, et al. Vet Parasitol. Frontiers in anthelmintic pharmacology

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  Catalog
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Keywords: PF 1022A  supplier, Parasite, inhibitors, activators

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