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Peimisine

Cat. No. M4265

All AbMole products are for research use only, cannot be used for human consumption.

Peimisine Structure
Synonym:

Ebeiensine

Size Price Availability Quantity
5mg USD 170  USD170 In stock
10mg USD 270  USD270 In stock
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Biological Activity

Peimisine (Ebeiensine) noncompetitively antagonizes M receptors in tracheal smooth muscle and thus inhibits Ach induced smooth muscle contraction. Peimisine also stimulates beta receptors and antagonizes the release of calcium, promoting the release of NO and thus relaxing the smooth muscles of the trachea to achieve antiasthmatic effects.

Chemical Information
Molecular Weight 427.62
Formula C27H41NO3
CAS Number 19773-24-1
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Xin Jin, et al. Study the mechanism of peimisine derivatives on NF-κB inflammation pathway on mice with acute lung injury induced by lipopolysaccharide

[2] Xiao Ruan, et al. Optimization of Supercritical Fluid Extraction of Total Alkaloids, Peimisine, Peimine and Peiminine from the Bulb of Fritillaria thunbergii Miq, and Evaluation of Antioxidant Activities of the Extracts

[3] Lihua Chen, et al. Pharmacokinetics, tissue distribution and excretion of peimisine in rats assessed by liquid chromatography-tandem mass spectrometry

[4] Feng Pan, et al. Peimisine and peiminine production by endophytic fungus Fusarium sp. isolated from Fritillaria unibracteata var. wabensis

[5] Shu-Yan Zheng, et al. A convenient and efficient one-pot conversion of peimisine into cyclopamine

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Keywords: Peimisine, Ebeiensine supplier, Mdm2, inhibitors, activators

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