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P7C3 is a Proneurogenic, neuroprotective compound. P7C3 Protects newborn neurons in the dentate gyrus and stimulates the growth of new neurons. Also enhances learning and memory in aged rats. Orally available and brain penetrant.
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Animal models | Mice |
Formulation | Dissolved in DMSO and diluted with 3% DMSO/10% cremophor EL/87.5% D5W (5% dextrose in water, pH 7.2). |
Dosages | ~40 mg/kg |
Administration | p.o.; i.p. |
Molecular Weight | 474.19 |
Formula | C21H18Br2N2O |
CAS Number | 301353-96-8 |
Solubility (25°C) | DMSO: ≥ 25 mg/mL |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Pieper AA, et al. Cell. Discovery of a proneurogenic, neuroprotective chemical.
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