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Ophiopogonin D', isolated from the tuber of Ophiopogon japonicus, is a rare naturally occurring C29 steroid glycoside. Ophiopogonin D' has cytotoxic activity against two human tumor cell lines mG-63 and SNU387. Ophiopogonin D' can induce necrotic apoptosis of prostate cancer LNCaP cells by activating RIPK1. IC50 were 3.09 μM and 3.63 μM, respectively. SIRT1 is activated in a dose-dependent manner by Ophiopogonin D'.
| Molecular Weight | 855.02 |
| Formula | C44H70O16 |
| CAS Number | 65604-80-0 |
| Solubility (25°C) | DMSO 10 mg/mL |
| Storage | 4°C, protect from light |
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