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Omarigliptin has weak ion channel activity (IC50 > 30 μM at IKr, Cav1.2, and Nav1.5). An expansive selectivity counterscreen (168 radioligand binding or enzymatic assays) was carried out at MDS Pharma. An IC50 > 10 μM was obtained in all assays.
J Biochem Mol Toxicol. 2021 Dec;35(12):e22914.
Omarigliptin protects against nonalcoholic fatty liver disease by ameliorating oxidative stress and inflammation
Omarigliptin purchased from AbMole
| Molecular Weight | 398.43 |
| Formula | C17H20F2N4O3S |
| CAS Number | 1226781-44-7 |
| Solubility (25°C) | DMSO ≥ 30 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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Products are for research use only. Not for human use. We do not sell to patients.
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