All AbMole products are for research use only, cannot be used for human consumption.
Oligomycin, an antifungal antibiotic, is an inhibitor of H+-ATP-synthase. Oligomycin blocks oxidative phosphorylation and the electron transport chain. Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells.
Biol Reprod. 2021 May 7;104(5):1114-1125.
Mitochondrial transfer from induced pluripotent stem cells rescues developmental potential of in vitro fertilized embryos from aging females
Oligomycin purchased from AbMole
| CAS Number | 1404-19-9 |
| Solubility (25°C) | Ethanol 30 mg/mL DMSO 20 mg/mL |
| Storage | -20°C, sealed |
[3] Abby Hearne, et al. Oligomycin-induced proton uncoupling
[4] Nikolaos D Georgakopoulos, et al. The pharmacological regulation of cellular mitophagy
| Related HIF Products |
|---|
| HIF-1α-IN-3
HIF-1α-IN-3 is a hypoxia-selective HIF-1α inhibitor. |
| HIF-2α-IN-2
HIF-2α-IN-2 is a hypoxia-inducible factors (HIF-2α) inhibitor, has an IC50 of 16 nM in scintillation proximity assay (SPA). |
| PRLX-93936 dihydrochloride
PRLX-93936 dihydrochloride is a HIF-1α inhibitor with anticancer activity. |
| 3-Aminobenzoic acid
3-Aminobenzoic acid is a hypoxia-inducible factor-1α (HIF-1α) inhibitor. |
| Steppogenin
Steppogenin is a potent inhibitor of HIF-1α and DLL4, with IC50 values of 0.56 and 8.46 μM, respectively. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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