Odoratisol A

Cat. No. M40070

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Quality Control & Documentation

Purity: >98.0%
COA
MSDS

Product Information

Biological Activity

Odoratisol A is found in Myristica fragrans.

Chemical Information

Molecular Weight	356.41
Formula	C21H24O5
CAS Number	891182-93-7
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

Conversion of different model animals based on BSA (PMID: 27057123)

Species	Mouse	Rat	Rabbit	Guinea pig	Hamster	Dog
Weight (kg)	0.02	0.15	1.8	0.4	0.08	10
Body Surface Area (m²)	0.007	0.025	0.15	0.05	0.02	0.5
K_m factor	3	6	12	8	5	20

Animal A (mg/kg) = Animal B (mg/kg) multiplied by	Animal B K_m
	Animal A K_m

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the K_m factor for a mouse and then divide by the K_m factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Wuttichai Jaidee et al. Fitoterapia. Antioxidant neolignans from the twigs and leaves of Mitrephora wangii HU

[2] Sajin K Francis et al. Nat Prod Res. Phytochemical investigation on Myristica fragrans stem bark

[3] Ulyana Muñoz Acuña et al. Food Chem. New acyclic bis phenylpropanoid and neolignans, from Myristica fragrans Houtt., exhibiting PARP-1 and NF-κB inhibitory effects

[4] Hyoungsu Kim et al. Org Lett. Stereoselective synthesis of tetrahydrofuran lignans via BF(3) x OEt(2)-promoted reductive deoxygenation/epimerization of cyclic hemiketal: synthesis of (-)-odoratisol C, (-)-futokadsurin A, (-)-veraguensin, (+)-fragransin A(2), (+)-galbelgin, and (+)-talaumidin

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Signaling Pathways

Odoratisol A

Quality Control & Documentation

Biological Activity

Chemical Information

Conversion of different model animals based on BSA (PMID: 27057123)

References

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