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OD36 

Cat. No. M28745

All AbMole products are for research use only, cannot be used for human consumption.

OD36  Structure

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Quality Control & Documentation
Biological Activity

OD36 is a RIPK2 inhibitor with an IC50 of 5.3 nM. OD36 is a macrocyclic inhibitor with potent binding to the ALK2 kinase ATP pocket. OD36 shows ALK2-directed activity with KDs of 37 nM.

Chemical Information
Molecular Weight 330.77
Formula C16H15ClN4O2
CAS Number 1638644-62-8
Form Solid
Solubility (25°C) DMSO 33.33 mg/mL (ultrasonic and warming and heat to 60°C)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Gonzalo Sánchez-Duffhues, et al. JBMR Plus. Development of Macrocycle Kinase Inhibitors for ALK2 Using Fibrodysplasia Ossificans Progressiva-Derived Endothelial Cells

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  Catalog
Abmole Inhibitor Catalog




Keywords: OD36  supplier, RIPK, inhibitors, activators

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