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OD36 is a RIPK2 inhibitor with an IC50 of 5.3 nM. OD36 is a macrocyclic inhibitor with potent binding to the ALK2 kinase ATP pocket. OD36 shows ALK2-directed activity with KDs of 37 nM.
Molecular Weight | 330.77 |
Formula | C16H15ClN4O2 |
CAS Number | 1638644-62-8 |
Form | Solid |
Solubility (25°C) | DMSO 33.33 mg/mL (ultrasonic and warming and heat to 60°C) |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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