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NVP-CLR457

Cat. No. M21093

All AbMole products are for research use only, cannot be used for human consumption.

NVP-CLR457  Structure

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Quality Control & Documentation
Biological Activity

NVP-CLR457 is an orally administered, non-CNS-penetrating, pan-IA-like phosphoinositide 3-kinase (PI3K) inhibitor.NVP-CLR457 shows a significant dose-dependent PK / PD / efficacy relationship.NVP-CLR457 has antitumor activity.

Chemical Information
Molecular Weight 455.39
Formula C18H20F3N7O4
CAS Number 1453082-52-4
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Robin A Fairhurst, et al. J Med Chem. Identification of NVP-CLR457 as an Orally Bioavailable Non-CNS-Penetrant pan-Class IA Phosphoinositol-3-Kinase Inhibitor

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  Catalog
Abmole Inhibitor Catalog




Keywords: NVP-CLR457 supplier, PI3K, inhibitors, activators

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