Certificate of Analysis

 

Product Name: NVP-CLR457
Catalog Number: M21093
CAS Number: 1453082-52-4

Physical and Chemical Properties
Formula: C18H20F3N7O4
Molecular Weight: 455.39
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: NVP-CLR457  Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: NVP-CLR457 is an orally administered, non-CNS-penetrating, pan-IA-like phosphoinositide 3-kinase (PI3K) inhibitor.NVP-CLR457 shows a significant dose-dependent PK / PD / efficacy relationship.NVP-CLR457 has antitumor activity.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.