Free shipping on all orders over $ 500

2-Aminoisobutyric acid

Cat. No. M19961
2-Aminoisobutyric acid Structure

NSC-16590; 2-Methylalanine; H-Aib-OH

Size Price Availability Quantity
100mg USD 46  USD46 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

2-Aminoisobutyric acid is a rare, non-protein amino acid and end-product of pyrimidine metabolism, excreted in urine and found in some antibiotics of fungal origin.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 103.12
Formula C4H9NO2
CAS Number 62-57-7
Purity >99%
Solubility Water 10.29 mg/mL
Storage at -20°C

[1] Takashi Misawa, et al. Chem Commun (Camb). Development of 2-aminoisobutyric acid (Aib)-rich cell-penetrating foldamers for efficient siRNA delivery

[2] Michal Douša. J Pharm Biomed Anal. Quantification of 2-aminoisobutyric acid impurity in enzalutamide bulk drug substance using hydrophilic interaction chromatography with fluorescence detection

[3] Kousuke Tsuchiya, et al. Chem Commun (Camb). Chemoenzymatic synthesis of polypeptides containing the unnatural amino acid 2-aminoisobutyric acid

[4] S Ogilvie-Villa, et al. J Bacteriol. Characterization of 2-aminoisobutyric acid transport in Neurospora crassa: a general amino acid permease-specific substrate

[5] J R Bergesse, et al. Toxicol Lett. Changes in 2-aminoisobutyric acid and cycloleucine uptake produced by 2,4-dichlorophenoxyacetic acid in Chinese hamster ovary cells

Related Products

SPH3127 is an oral direct renin inhibitor (DRI) that is being developed for hypertension. The renin-angiotensin-aldosterone system is responsible for the regulation of blood pressure.


SAfit2 is a potent inhibitor of FK506-binding protein 51 (FKBP51) with a Ki value of 6 nM. SAfit2 has been used as a potential agent in the study of major depression, obesity, and chronic pain.

lipid 10a

“lipid 10a” (Arcturus tunable lipid for RNA drug delivery).

BAY 1214784

BAY 1214784 is a potent, selective and orally active antagonist of the human gonadotropin-releasing hormone receptor (hGnRH-R).BAY 1214784 has the potential to be studied in uterine fibroids.


Abmole Inhibitor Catalog

Keywords: 2-Aminoisobutyric acid, NSC-16590; 2-Methylalanine; H-Aib-OH supplier, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.