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NRD167 (Et-29) is a potent and selective SIRT5 inhibitor with Ki value of 40 nM.
| Molecular Weight | 666.83 |
| Formula | C34H46N6O6S |
| CAS Number | 2166487-23-4 |
| Solubility (25°C) | DMSO 100 mg/mL |
| Storage | -20°C, protect from light, sealed |
[1] Meng Li, et al. Blood Cancer Discov. Non-oncogene Addiction to SIRT5 in Acute Myeloid Leukemia
| Related Sirtuin Products |
|---|
| SIRT1-IN-1
SIRT1-IN-1 is a selective SIRT1 inhibitor with an IC50 of 0.205 μM. |
| Sirtuin-1 inhibitor 1
Sirtuin-1 inhibitor 1 is an inhibitor of Sirtuin-1 that plays important roles in obesity-induced diabetes and aging-related diseases. |
| ADTL-SA1215
ADTL-SA1215 is a first-in-class, specific small molecule activator of SIRT3 that modulates autophagy in triple-negative breast cancer. |
| SIRT2/6-IN-1
SIRT2/6-IN-1 is a SIRT6/SIRT2 inhibitor, with IC50s of 106 μM and 114 μM. |
| SIRT6-IN-2
SIRT6-IN-2 is a selective SIRT6 inhibitor (IC50: 34 μM). |
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