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NIK SMI1 is a highly selective and potent NF-κB-inducing kinase (NIK) inhibitor. NIK SMI1 exhibits selective inhibition of LTβR-dependent p52 translocation and transcription of NF-κB2 related genes. NIK SMI1 inhibits BAFF signaling and reduces splenic marginal zone B cells in vivo.
| Molecular Weight | 365.38 |
| Formula | C20H19N3O4 |
| CAS Number | 1660114-31-7 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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