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NF-κΒ activator 2 is a potent and orally active NF-ҡB activator, with an EC50 of 1.58 μM. NF-κΒ activator 2 induces SOD2 through increasing NF-ҡB expression and activation. NF-κΒ activator 2 can be used for the research of amyotrophic lateral sclerosis (ALS).
Molecular Weight | 298.27 |
Formula | C16H11FN2O3 |
CAS Number | 2375281-44-8 |
Form | Solid |
Solubility (25°C) | DMSO 250 mg/mL (ultrasonic) |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] Nasser Hashemi Goradel, et al. J Cell Physiol. Cyclooxygenase-2 in cancer: A review
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